Abstract Deep learning has proven capable of automating key aspects of histopathologic analysis.However, its context-specific nature and continued reliance on large expert-annotated training datasets hinders the development of a critical mass of applications to garner widespread adoption in clinical/research workflows.Here, we present an online col
Abstract The IR dynamics of SYK is that of Chemicals and Solutions the Schwarzian theory, the effective theory of broken reparametrization invariance.In the double scaling limit, SYK is completely solvable by chord diagrams, whose generating functional is a bilocal Liouville theory.At low temperatures a set of modes in this description becomes soft
Abstract Background Top-down homogeneous multiplexed tandem mass (HomMTM) spectra are generated from modified proteoforms of the same protein with different post-translational modification patterns.They are frequently observed in the analysis of ultramodified proteins, some proteoforms of which have similar molecular weights and cannot be well sepa
Polyethylene glycol (PEG) surface conjugations are widely employed to render passivating properties to nanoparticles in biological applications.The benefits of surface passivation by PEG are reduced protein adsorption, diminished non-specific interactions, and improvement in pharmacokinetics.However, the limitations of PEG passivation remain an act
Chordomas are rare malignant neoplasms arising from vestigial remnants of the embryonic notochord.Approximately 55-70% of chordomas develop within the vertebral column.Their affinity to develop within the bones of the axial skeleton and propensity to locally invade and recur makes them challenging candidates for complete surgical excision.Adjuvant